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Diabetologia 1993;36: 225–228. 126 Barker DJ, Hales CN, Fall CH, Osmond C, Phipps K, Clark PM: Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 1993;36:62–67. 127 Hales CN, Barker DJ, Clark PM, et al: Fetal and infant growth and impaired glucose tolerance at age 64. BMJ 1991;303:1019–1022. 128 Jackson AA: Nutrients, growth, and the development of programmed metabolic function. Adv Exp Med Biol 2000;478:41–55.

69 Campbell H, Rudan I: Interpretation of genetic association studies in complex disease. Pharmacogenomics J 2002;2:349–360. 70 McCarthy MI, Abecasis GR, Cardon LR, et al: Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet 2008;9:356–369. 71 Sladek R, Rocheleau G, Rung J, et al: A genomewide association study identifies novel risk loci for type 2 diabetes. Nature 2007;445:881–885. 72 Saxena R, Voight BF, Lyssenko V, et al: Genomewide association analysis identifies loci for type 2 diabetes and triglyceride levels.

136 Sayer AA, Cooper C, Evans JR, et al: Are rates of ageing determined in utero? Age Ageing 1998;27: 579–583. 137 Kuh D, Bassey J, Hardy R, Aihie Sayer A, Wadsworth M, Cooper C: Birth weight, childhood size, and muscle strength in adult life: evidence from a birth cohort study. Am J Epidemiol 2002;156:627–633. 138 Vickers MH, Breier BH, McCarthy D, Gluckman PD: Sedentary behavior during postnatal life is determined by the prenatal environment and exacerbated by postnatal hypercaloric nutrition.

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