By A A. Johansen (auth.), B. C. Morson (eds.)
Immunology, in all its aspects of immunochemistry, humoral immunity, mobile immunity, immunodiagnosis, and immunotherapy, is presently the main swiftly advancing self-discipline of scientific and experimental oncology. yet as in such a lot constructing matters, it's consistently beset with difficulties of method and nomenclature, either one of that are usually intertwined. Indicative of this challenge are our round definitions of antigen and antibody. one other fre quent challenge is using the phrases "specific" and "associated" whilst characterizing re activities to tumors or the antigenic homes of neoplasms. whilst utilized to melanoma, those phrases are patently very established upon the equipment used to illustrate those characteristics. certainly, the very assorted nature and multitude of varieties of melanoma avoid our making gen eralizations or specific statements concerning tumor "specificity. " comparable difficulties come up while one considers that many antigens present in malignant tumors percentage definite houses with embryonic or fetal tissues. First, those observations emphasize a scarcity of actual tumor specificity, for which cause the class of oncofetal antigens has been tested. moment, even if such antigens are really oncofetal relies on the strategy of detection used, and it's been came across that right here too specificity decreases because the antigen assay raises in sen sitivity. therefore, even if ingredients should be actually oncofetal in nature nonetheless is still a question of dialogue, and such phrases needs to for this reason be utilized in an operational sense.