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By Robert W. Schrier
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Additional resources for Atlas Of Diseases Of The Kidney
7. Gonzalez-Campoy JM, Knox FG: Integrated responses of the kidney to alterations in extracellular fluid volume. In The Kidney: Physiology and Pathophysiology, edn 2. Edited by Seldin DW, Giebisch G. New York: Raven Press; 1992:2041–2097. 14. Skott O, Briggs JP: Direct demonstration of macula densa mediated renin secretion. Science 1987, 237:1618–1620. 15. Hall JE, Guyton AC: Changes in renal hemodynamics and renin release caused by increased plasma oncotic pressure. Am J Physiol 1976, 231:1550.
34. Escalante B, Erlij D, Falck JR, McGiff JC: Effect of cytochrome P450 arachidonate metabolites on ion transport in rabbit kidney loop of Henle. Science 1991, 251:799–802. 35.
Although plasma renin activity in patients with nephrotic syndrome is not suppressed to the same degree, the absence of PRA elevation in these patients suggests that primary renal Na retention plays a significant role in the pathogenesis of Na retention in NS as well. ) FIGURE 2-38 Sites of sodium (Na) reabsorption along the nephron in control and nephrotic rats (induced by puromycin aminonucleoside [PAN]). The glomerular filtration rates (GFR) in normal and nephrotic rats are shown by the hatched bars.